As part of an exciting and very succcessful exhibit at the Analytica trade show, we had demonstrated our new collaboration software in action. Visitors could watch the online collaboration unfold in front of two screens, showing two independent but synchronized workplaces for the processing and exchange of biological data.

GIT Verlag kindly features an interview with our business developer Elena Ulyanova and Dominik Lindner, one of our software engineers working on the software. Watch the video here.

Meet us in Hall A3, booth 565. We will present our services at Analytica 2012. The trade show takes place April 17-20, 2012, in Munich.

At the trade show, we will present our gene synthesis and protein expression services, as well as a new collaboration software for the remote interaction in biological projects.

Entelechon has published a free online tool for the calculation of the complexity of randomized mutant libraries.
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Entelechon has 12 years of experience in gene synthesis. We have
designed thousands of genes and we improved our gene optimization
algorithm to get only the best possible sequences, resulting in highest
protein expression. Benefit from our experience.

Expression Insurance Service Package:

• Analysis of the sequence*
• Gene optimization
• Gene synthesis
• Cloning and expression in E.coli on a 1 mL scale
• Report on expression and solubility
• Screening for the best performing clone

Positive protein expression:

You receive an optimized synthetic gene, Data report confirmation of the
protein expression and the best performing bacteria clone for the price
Eur 990 + 0.69 EUR/bp for gene synthesis.

Negative protein expression:

Even the best way optimized genes sometimes do not express for objective
biological reasons. When expression is not successful, i.e. there is no
detectable product after induction or the yield is less than 1 mg / L, you receive
Data report and you pay just 0.39 EUR/bp for gene synthesis.

Minimize your protein expression risks and expenses!

Entelechon’s managing director Markus Fischer will be present at the BIO Europe meeting in Düsseldorf, Germany. The event takes place from October 31 to November 02 and is the perfect opportunity to discuss how you can leverage our fee-for-services for your research and development projects.

One of the main focuses will be Entelechon’s recently launched codon-precision mutant libraries, which are based on shuffled codons and which are free from undesired codons or stop codons. Compared to conventional, single nucleotide randomized libraries, Entelechon’s codon-precision libraries can reduce the effort required for screening – and thus your turn around time and costs – significantly.

In addition, we will be happy to discuss our service portfolio – including custom gene synthesis, bioinformatics, and protein expression – with you at BIO Europe. If you are interested in quantitative proteomics or biomarker discovery, please ask about the QconCAT technology of our subsidiary PolyQuant.

In order to arrange for a meeting at the BIO Europe, please either use the official Partnering Platform, or contact us.

Based on an innovative new technology developed in-house at Entelechon, we offer codon-precision mutation libraries effective immediately. These libraries contain randomized positions where a set of multiple alternative codons is incorporated into the gene sequence.
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Entelechon’s managing director Markus Fischer will participate in HUPO’s 10th annual world congress at Geneva, starting September 4. He will be representing Entelechon’s subsidiary PolyQuant at the event, and will engage in discussions with industry leaders and academics partners as how the QconCAT technology can be applied to the problem of defining and quantifying the human plasma proteome.

The plasma proteome is one of the most interesting targets for personalized medicine, and a promising resource for diagnostics. However, the vast concentration range of different plasma proteins – reaching from the very abundant immune globulines and serum albumine to faint traces of proteins leaking from damaged epithelial cells, spanning over 12 log units – make it very difficult to get an accurate readout of small changes in low-abundant proteins.

The QconCAT technology is particularly suited to tackle this problem, and the HUPO meeting will be an excellent opportunity to discuss its application to the analysis of the plasma proteome. For more information, please get in touch with us via the contact form.

With tumor therapy becoming increasingly a focus of researchers and investors alike, the demand for effective tumor markers grows strongly. The molecular biology and proteomics service provider Entelechon has started an initiative for the development of tumor marker discovery kits. The project is funded by the German BMBF (Ministry of Education and Research) and aims at the design of a combined depletion and enrichment kit specific to a panel of potential tumor markers. The press release can be found here.

Entelechon has moved into new facilities in May.  We are fully operational again, and are happy to say that the new site allows us to provide even better services to our clients. With more than double the floor space and state-of-the-art molecular biology lab, you can expect the same commitment to customer satisfaction, but also quicker turn around times and an expanded service portfolio in the near future.

The new coordinates are:

Entelechon GmbH / PolyQuant GmbH
Industriestr. 1
93077 Bad Abbach
Germany

Tel. +49 (9405) 96999-10
Fax  +49 (9405) 96999-28